Gene
fgl1
- ID
- ZDB-GENE-130815-1
- Name
- fibrinogen-like 1
- Symbol
- fgl1 Nomenclature History
- Previous Names
-
- fgl1a (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to be involved in negative regulation of T cell activation and regulation of immune response. Predicted to act upstream of or within adaptive immune response and blood coagulation. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Orthologous to human FGL1 (fibrinogen like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Choudhuri et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020837 | Fibrinogen, conserved site |
| Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
| Family | IPR037579 | Fibrinogen/angiopoietin-like |
| Homologous_superfamily | IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 |
| Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | Fibrinogen/angiopoietin-like | Fibrinogen, conserved site | Fibrinogen-like, C-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A140LG86 | InterPro | 307 | |||||
| UniProtKB:A0A8M1QVF0 | InterPro | 307 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-238L1 | ZFIN Curated Data | |
| Contained in | BAC | DKEYP-46F3 | ZFIN Curated Data | |
| Contained in | BAC | DKEYP-51D11 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001923551 (1) | 1192 nt | ||
| Genomic | GenBank:BX530719 (1) | 197865 nt | ||
| Polypeptide | UniProtKB:A0A140LG86 (1) | 307 aa |
- Gasanov, E.V., Jędrychowska, J., Kuźnicki, J., Korzh, V. (2021) Evolutionary context can clarify gene names: Teleosts as a case study. BioEssays : news and reviews in molecular, cellular and developmental biology. 43(6):e2000258
- Li, Y., Lv, Y., Bian, C., You, X., Shi, Q. (2020) Molecular evolution of melatonin receptor genes (mtnr) in vertebrates and its shedding light on mtnr1c. Gene. 769:145256
- Choudhuri, A., Maitra, U., and Evans, T. (2013) Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110(24):9818-9823
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