Gene

kcnj10a

ID
ZDB-GENE-130726-1
Name
potassium inwardly rectifying channel subfamily J member 10a
Symbol
kcnj10a Nomenclature History
Previous Names
  • Kir4.1a (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits inward rectifier potassium channel activity. Involved in kidney development; larval locomotory behavior; and swimming. Predicted to localize to integral component of membrane. Is expressed in several structures, including central nervous system; opercular flap; pleuroperitoneal region; retinal inner nuclear layer; and scale. Used to study EAST syndrome. Human ortholog(s) of this gene implicated in EAST syndrome and autosomal recessive nonsyndromic deafness 4. Orthologous to human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnj10a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 4 Alliance Enlarged vestibular aqueduct, digenic 600791
EAST syndrome Alliance SESAME syndrome 612780
Associated With kcnj10a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR040445 Potassium channel, inwardly rectifying, transmembrane domain
Domain IPR041647 Inward rectifier potassium channel, C-terminal
Family IPR003269 Potassium channel, inwardly rectifying, Kir1.2
Family IPR016449 Potassium channel, inwardly rectifying, Kir
Homologous_superfamily IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
Homologous_superfamily IPR014756 Immunoglobulin E-set
Domain Details Per Protein
Protein Length Immunoglobulin E-set Inward rectifier potassium channel, C-terminal Potassium channel, inwardly rectifying, Kir Potassium channel, inwardly rectifying, Kir1.2 Potassium channel, inwardly rectifying, Kir, cytoplasmic Potassium channel, inwardly rectifying, transmembrane domain
UniProtKB:E7FD27 425
UniProtKB:R5A7X2 41
UniProtKB:A0A0G2KRC3 420
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations