Gene
fyco1b
- ID
- ZDB-GENE-130326-1
- Name
- FYVE and coiled-coil domain autophagy adaptor 1b
- Symbol
- fyco1b Nomenclature History
- Previous Names
-
- zmp:0000000838 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Predicted to be involved in plus-end-directed vesicle transport along microtubule and positive regulation of autophagosome maturation. Human ortholog(s) of this gene implicated in cataract 18. Orthologous to human FYCO1 (FYVE and coiled-coil domain autophagy adaptor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cataract 18 | Alliance | Cataract 18, autosomal recessive | 610019 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000306 | FYVE zinc finger |
| Domain | IPR004012 | RUN domain |
| Domain | IPR009038 | GOLD domain |
| Domain | IPR017455 | Zinc finger, FYVE-related |
| Domain | IPR047336 | FYCO1, RUN domain |
| Domain | IPR047337 | FYCO1, FYVE domain |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036598 | GOLD domain superfamily |
| Homologous_superfamily | IPR037213 | RUN domain superfamily |
Domain Details Per Protein
| Protein | Length | FYCO1, FYVE domain | FYCO1, RUN domain | FYVE zinc finger | GOLD domain | GOLD domain superfamily | RUN domain | RUN domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1RDW0
|
|||||||||||
|
UniProtKB:A0A8M6YUP3
|
1298 | ||||||||||
|
UniProtKB:A0A8M1RLQ4
|
1346 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance