Gene
spsb3b
- ID
- ZDB-GENE-121226-2
- Name
- splA/ryanodine receptor domain and SOCS box containing 3b
- Symbol
- spsb3b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human SPSB3 (splA/ryanodine receptor domain and SOCS box containing 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa37959 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | Concanavalin A-like lectin/glucanase domain superfamily | F-box/SPRY and SOCS box protein families | Immunoglobulin-like domain | SPRY domain | SPRY domain-containing SOCS box protein 3, SPRY domain |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9P604 | InterPro | 334 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
spsb3b-201
(1)
|
Ensembl | 884 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-171A6 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_021470242 (1) | 1041 nt | ||
Genomic | GenBank:CU929145 (1) | 90957 nt | ||
Polypeptide | UniProtKB:A0A8M9P604 (1) | 334 aa |
- Swaminathan, A., Gliksberg, M., Anbalagan, S., Wigoda, N., Levkowitz, G. (2023) Stress resilience is established during development and is regulated by complement factors. Cell Reports. 42:111973111973
- Martínez, R., Navarro-Martín, L., Luccarelli, C., Codina, A.E., Raldúa, D., Barata, C., Tauler, R., Piña, B. (2019) Unravelling the mechanisms of PFOS toxicity by combining morphological and transcriptomic analyses in zebrafish embryos. The Science of the total environment. 674:462-471
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