Gene
clstn2b
- ID
- ZDB-GENE-121214-77
- Name
- calsyntenin 2b
- Symbol
- clstn2b Nomenclature History
- Previous Names
-
- si:ch211-276c2.2
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and synapse. Predicted to be active in cell surface and postsynaptic membrane. Orthologous to human CLSTN2 (calsyntenin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa10780 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa17939 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa35982 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa42616 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cadherin-like | Cadherin-like superfamily | Calsyntenin, C-terminal | Concanavalin A-like lectin/glucanase domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:R4GEC6 | InterPro | 917 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-276c2.2-201
(1)
|
Ensembl | 3,490 nt | ||
| ncRNA |
si:ch211-276c2.2-002
(1)
|
Ensembl | 398 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-276C2 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-230I18 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_693062 (1) | 3545 nt | ||
| Genomic | GenBank:CR848665 (1) | 158232 nt | ||
| Polypeptide | UniProtKB:R4GEC6 (1) | 917 aa |
- Comparative Orthology
- Alliance
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Crespo, B., Lan-Chow-Wing, O., Rocha, A., Zanuy, S., Gómez, A. (2013) foxl2 and foxl3 are two ancient paralogs that remain fully functional in teleosts. General and comparative endocrinology. 194:81-93
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