Gene
patl2
- ID
- ZDB-GENE-121214-350
- Name
- PAT1 homolog 2
- Symbol
- patl2 Nomenclature History
- Previous Names
-
- si:ch211-103b1.2
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to be located in cytoplasm and nucleus. Predicted to be active in P-body. Orthologous to human PATL2 (PAT1 homolog 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Oocyte/zygote/embryo maturation arrest 4 | 617743 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | mRNA decay factor PAT1 domain | Pat1-like |
|---|---|---|---|---|
| UniProtKB:E7FAC4 | InterPro | 714 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
patl2-203
(1)
|
Ensembl | 3,591 nt | ||
| mRNA |
patl2-204
(1)
|
Ensembl | 3,579 nt | ||
| mRNA |
si:ch211-103b1.2-201
(1)
|
Ensembl | 2,877 nt | ||
| ncRNA |
si:ch211-103b1.2-002
(1)
|
Ensembl | 539 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-103B1 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_678169 (1) | |||
| Genomic | GenBank:CT030151 (1) | 169985 nt | ||
| Polypeptide | UniProtKB:E7FAC4 (1) | 714 aa |
- Comparative Orthology
- Alliance
- Jamieson-Lucy, A.H., Kobayashi, M., James Aykit, Y., Elkouby, Y., Escobar-Aguirre, M., Vejnar, C., Giraldez, A., Mullins, M.C. (2022) A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and Cirbpb. Developmental Biology. 484:1-11
- Cheung, C.T., Nguyen, T.V., Le Cam, A., Patinote, A., Journot, L., Reynes, C., Bobe, J. (2019) What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization. BMC Genomics. 20:584
- Qian, J., Han, Y., Li, J., Zhang, J., Hu, C. (2018) Toxic effect prediction of cefatirizine amidine sodium and its impurities by structure-toxicity relationship of cephalosporins. Toxicology in vitro : an international journal published in association with BIBRA. 46:137-147
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