Gene

pfkla

ID
ZDB-GENE-121207-1
Name
phosphofructokinase, liver a
Symbol
pfkla Nomenclature History
Previous Names
  • pfkl
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable 6-phosphofructokinase activity and fructose-6-phosphate binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to act upstream of or within glycolytic process and phosphorylation. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Predicted to be active in membrane. Is expressed in liver. Orthologous to human PFKL (phosphofructokinase, liver type).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pfkla Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hemolytic anemia due to phosphofructokinase deficiency
1 - 1 of 1
Associated With pfkla Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR015912 Phosphofructokinase, conserved site
Domain IPR000023 Phosphofructokinase domain
Family IPR009161 ATP-dependent 6-phosphofructokinase, eukaryotic-type
Family IPR022953 ATP-dependent 6-phosphofructokinase
Family IPR041914 ATP-dependent 6-phosphofructokinase, vertebrate-type
1 - 5 of 6 Show all
Domain Details Per Protein
Protein Additional Resources Length ATP-dependent 6-phosphofructokinase ATP-dependent 6-phosphofructokinase, eukaryotic-type ATP-dependent 6-phosphofructokinase, vertebrate-type Phosphofructokinase, conserved site Phosphofructokinase domain Phosphofructokinase superfamily
UniProtKB:E7F9M6 InterPro 780
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pfkla-201 (1)
Ensembl
Ensembl 3,196 nt
ZFIN BLAST
mRNA pfkla-202 (1)
Ensembl
Ensembl 2,456 nt
ZFIN BLAST
ncRNA pfkla-002 (1)
Ensembl
Ensembl 514 nt
ZFIN BLAST
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations
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