Gene
pappaa
- ID
- ZDB-GENE-121113-1
- Name
- pregnancy-associated plasma protein A, pappalysin 1a
- Symbol
- pappaa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable metalloendopeptidase activity. Acts upstream of or within several processes, including chondrocyte differentiation; habituation; and insulin-like growth factor receptor signaling pathway. Predicted to be active in extracellular space. Is expressed in CNS interneuron; Meckel's cartilage; and cranial ganglion. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human PAPPA (pappalysin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Concanavalin A-like lectin/glucanase domain superfamily | Fibronectin type III superfamily | LamG-like jellyroll fold | Metallopeptidase, catalytic domain superfamily | Myxococcus cysteine-rich repeat | Notch domain | Pappalysin-1/2 | Peptidase M43, pregnancy-associated plasma-A | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:M1XYM1 | InterPro | 1629 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pappaa-201
(1)
|
Ensembl | 5,582 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available