Gene

alpk3b

ID

ZDB-GENE-121101-3

Name

alpha-kinase 3b

Symbol

alpk3b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in cardiac muscle cell development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human ALPK3 (alpha kinase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With alpk3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cardiomyopathy, familial hypertrophic 27	618052

Associated With alpk3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin subtype
Domain	IPR004166	Alpha-type protein kinase, alpha-kinase domain
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Alpha-type protein kinase, alpha-kinase domain	Immunoglobulin I-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype	Immunoglobulin subtype 2	Protein kinase-like domain superfamily
UniProtKB:A0A8M9PZ45 InterPro	1934
UniProtKB:A0A8M9PPS8 InterPro	1921

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	alpk3b-201 (1) Ensembl	Havana	6122 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations