Gene

aldh3a1

ID
ZDB-GENE-120823-1
Name
aldehyde dehydrogenase 3 family, member A1
Symbol
aldh3a1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable 3-chloroallyl aldehyde dehydrogenase activity and aldehyde dehydrogenase (NAD+) activity. Acts upstream of or within glucose homeostasis. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in brain and eye. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome and arteriosclerosis. Orthologous to several human genes including ALDH3A2 (aldehyde dehydrogenase 3 family member A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Lou et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldh3a1 Human Ortholog
No data available
Associated With aldh3a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016160 Aldehyde dehydrogenase, cysteine active site
Conserved_site IPR029510 Aldehyde dehydrogenase, glutamic acid active site
Domain IPR015590 Aldehyde dehydrogenase domain
Family IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
Homologous_superfamily IPR016161 Aldehyde/histidinol dehydrogenase
Homologous_superfamily IPR016162 Aldehyde dehydrogenase, N-terminal
Homologous_superfamily IPR016163 Aldehyde dehydrogenase, C-terminal
Domain Details Per Protein
Protein Length Aldehyde dehydrogenase, C-terminal Aldehyde dehydrogenase, cysteine active site Aldehyde dehydrogenase domain Aldehyde dehydrogenase, glutamic acid active site Aldehyde dehydrogenase NAD(P)-dependent Aldehyde dehydrogenase, N-terminal Aldehyde/histidinol dehydrogenase
UniProtKB:X1WBM4 489
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations