Gene
rlim
- ID
- ZDB-GENE-120809-2
- Name
- ring finger protein, LIM domain interacting
- Symbol
- rlim Nomenclature History
- Previous Names
-
- rnf12 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in nucleus. Is expressed in mesoderm. Human ortholog(s) of this gene implicated in Tonne-Kalscheuer syndrome. Orthologous to human RLIM (ring finger protein, LIM domain interacting).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Tonne-Kalscheuer syndrome | Alliance | Tonne-Kalscheuer syndrome | 300978 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | RING finger E3 ubiquitin-protein ligase | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|
| UniProtKB:E7FH41 | InterPro | 638 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance