ZFIN is now using GRCz12tu for Genomic Data
Gene
uts2d
- ID
- ZDB-GENE-120530-1
- Name
- urotensin 2 domain containing
- Symbol
- uts2d Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable hormone activity. Predicted to be located in extracellular region. Is expressed in central nervous system and spinal cord neural tube. Orthologous to human UTS2B (urotensin 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Quan et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Quan et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| mhn1 | Allele with one deletion | Unknown | Unknown | CRISPR |
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| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-uts2d | (2) | |
| CRISPR2-uts2d | (2) | |
| CRISPR3-uts2d | Gaillard et al., 2023 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Urotensin-2B | Urotensin II |
|---|---|---|---|---|
| UniProtKB:H9T836 | InterPro | 115 |
1 - 1 of 1
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-117L17 |
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- Genome Browsers
| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001258318 (1) | 612 nt | ||
| Genomic | GenBank:BX936311 (1) | 192750 nt | ||
| Polypeptide | UniProtKB:H9T836 (1) | 115 aa |
- Gaillard, A.L., Mohamad, T., Quan, F.B., de Cian, A., Mosimann, C., Tostivint, H., Pézeron, G. (2023) Urp1 and Urp2 act redundantly to maintain spine shape in zebrafish larvae. Developmental Biology. 496:36-51
- Quan, F.B., Gaillard, A.L., Alejevski, F., Pézeron, G., Tostivint, H. (2021) Urotensin II-related peptide (Urp) is expressed in motoneurons in zebrafish, but is dispensable for locomotion in larva. Peptides. 146:170675
- Rabinowitz, J.S., Robitaille, A.M., Wang, Y., Ray, C.A., Thummel, R., Gu, H., Djukovic, D., Raftery, D., Berndt, J.D., Moon, R.T. (2017) Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 114(5):E717-E726
- Quan, F.B., Bougerol, M., Rigour, F., Kenigfest, N.B., and Tostivint, H. (2012) Characterization of the true ortholog of the urotensin II-related peptide (URP) in teleosts. General and comparative endocrinology. 177(1):205-212
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