Gene
arhgap35a
- ID
- ZDB-GENE-120516-2
- Name
- Rho GTPase activating protein 35a
- Symbol
- arhgap35a Nomenclature History
- Previous Names
-
- arhgap35
- wu:fb33f06
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in Rho protein signal transduction; regulation of axonogenesis; and regulation of cell size. Predicted to be located in several cellular components, including cytoskeleton; nucleus; and plasma membrane. Predicted to be active in cytosol. Orthologous to human ARHGAP35 (Rho GTPase activating protein 35).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Lippincott et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Lippincott et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000198 | Rho GTPase-activating protein domain |
| Domain | IPR002713 | FF domain |
| Domain | IPR032835 | Rho GTPase-activating protein, FF domain |
| Domain | IPR039006 | Rho GTPase-activating protein, pG2 domain |
| Domain | IPR039007 | Rho GTPase-activating protein, pG1 domain |
| Domain | IPR045786 | Rho GTPase-activating protein, pG1 and pG2 domain |
| Family | IPR001806 | Small GTPase |
| Family | IPR051978 | Rho GTPase-activating domain-containing protein |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036517 | FF domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | FF domain | FF domain superfamily | P-loop containing nucleoside triphosphate hydrolase | Rho GTPase-activating domain-containing protein | Rho GTPase-activating protein domain | Rho GTPase-activating protein, FF domain | Rho GTPase-activating protein, pG1 and pG2 domain | Rho GTPase-activating protein, pG1 domain | Rho GTPase-activating protein, pG2 domain | Rho GTPase activation protein | Small GTPase |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F8G5 | InterPro | 1536 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgap35a-201
(1)
|
Ensembl | 7,889 nt | ||
| mRNA |
arhgap35a-202
(1)
|
Ensembl | 8,415 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance