ZFIN is now using GRCz12tu for Genomic Data
Gene

sema4bb

ID
ZDB-GENE-120503-1
Name
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
Symbol
sema4bb Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human SEMA4B (semaphorin 4B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa11494Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa13494Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa44667Allele with one point mutationUnknownUnknownENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With sema4bb Human Ortholog
No data available
Associated With sema4bb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR016201 PSI domain
Family IPR027231 Semaphorin
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length Plexin repeat PSI domain Sema domain Sema domain superfamily Semaphorin WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:F1QU86 InterPro 849
UniProtKB:A0A8M2BG75 InterPro 849
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Transcripts
Genome Browsers
Genome Assembly: GRCz11Chromosome: 7
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sema4bb-201 (1)
Ensembl
Ensembl 6,393 nt
ZFIN BLAST
mRNA sema4bb-202 (1)
Ensembl
Ensembl 746 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-107O10ZFIN Curated Data
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Sequences
Genome Browsers
Genome Assembly: GRCz12tuChromosome: 7
Type Accession # Genome Assembly Length (nt/aa) Analysis
RNARefSeq:XM_073908583 (1)GRCz12tu5982 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:CR381651 (1)154341 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M2BG75 (1)849 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanSEMA4B15
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseSema4b7
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
TSV
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