Gene
shank2a
- ID
- ZDB-GENE-120215-55
- Name
- SH3 and multiple ankyrin repeat domains 2a
- Symbol
- shank2a Nomenclature History
- Previous Names
-
- si:ch1073-450f2.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have GKAP/Homer scaffold activity and ionotropic glutamate receptor binding activity. Predicted to be involved in several processes, including nervous system development; positive regulation of synaptic transmission; and regulation of AMPA receptor activity. Predicted to colocalize with ionotropic glutamate receptor complex and postsynaptic membrane.
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001478 | PDZ domain |
Domain | IPR001660 | Sterile alpha motif domain |
Domain | IPR041489 | PDZ domain 6 |
Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
Homologous_superfamily | IPR036034 | PDZ superfamily |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | PDZ domain | PDZ domain 6 | PDZ superfamily | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PAP9
|
1707 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
si:ch1073-450f2.1-202
(1)
|
Havana | 1369 nt | |
mRNA |
si:ch1073-450f2.1-203
(1)
|
Havana | 4367 nt |
Interactions and Pathways
No data available
Plasmids
No data available