Gene

prkcdb

ID
ZDB-GENE-111129-1
Name
protein kinase C, delta b
Symbol
prkcdb Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to localize to nucleus and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3; fatty liver disease; and hypertension. Orthologous to human PRKCD (protein kinase C delta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkcdb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autoimmune lymphoproliferative syndrome type 3 Alliance Autoimmune lymphoproliferative syndrome, type III 615559
Associated With prkcdb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR017892 Protein kinase, C-terminal
Domain IPR020454 Diacylglycerol/phorbol-ester binding
Family IPR014376 Protein kinase C, delta/epsilon/eta/theta types
Family IPR027436 Protein kinase C, delta
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR046349 C1-like domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C1-like domain superfamily C2 domain superfamily Diacylglycerol/phorbol-ester binding Protein kinase, ATP binding site Protein kinase C, delta Protein kinase C, delta/epsilon/eta/theta types Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A8M9QDJ7
InterPro
685
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA prkcdb-201 (1)
Ensembl
Havana 5133 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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