Gene
rasgrf2a
- ID
- ZDB-GENE-111128-1
- Name
- Ras protein-specific guanine nucleotide-releasing factor 2a
- Symbol
- rasgrf2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Orthologous to human RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Conserved_site | IPR019804 | Ras guanine-nucleotide exchange factor, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
| Family | IPR008937 | Ras-like guanine nucleotide exchange factor |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | IQ motif, EF-hand binding site | PH-like domain superfamily | Pleckstrin homology domain | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine-nucleotide exchange factor, conserved site | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor | Ras-like guanine nucleotide exchange factor, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FBN7
|
||||||||||||
|
UniProtKB:A0A8M3B5Z6
|
1274 | |||||||||||
|
UniProtKB:A0A8M9PT33
|
208 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available