Gene

cers4b

ID
ZDB-GENE-110719-2
Name
ceramide synthase 4b
Symbol
cers4b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane and nucleus. Is expressed in brain; digestive system; myotome; and pectoral fin. Orthologous to human CERS4 (ceramide synthase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa1656Allele with one point mutationUnknownSplice SiteENU
sa9557Allele with one point mutationUnknownPremature StopENU
sa25943Allele with one point mutationUnknownSplice SiteENU
sa39954Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With cers4b Human Ortholog
No data available
Associated With cers4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001356 Homeodomain
Domain IPR006634 TRAM/LAG1/CLN8 homology domain
Family IPR016439 Sphingosine N-acyltransferase Lag1/Lac1-like
Homologous_superfamily IPR009057 Homedomain-like superfamily
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Domain Details Per Protein
Protein Additional Resources Length Homedomain-like superfamily Homeodomain Sphingosine N-acyltransferase Lag1/Lac1-like TRAM/LAG1/CLN8 homology domain
UniProtKB:A0A8M2BAR8 InterPro 402
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 2
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cers4b-201 (1) Ensembl 1,143 nt
mRNA cers4b-202 (1) Ensembl 737 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-126I18ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanCERS419
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
MouseCers48
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
Citations
1 - 8 of 8
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