Gene
mtbl
- ID
- ZDB-GENE-110414-3
- Name
- metallothionein-B-like
- Symbol
- mtbl Nomenclature History
- Previous Names
-
- smtB (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Acts upstream of or within angiogenesis. Is expressed in several structures, including brain; heart; liver; medial longitudinal fasciculus; and pleuroperitoneal region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Teoh et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Schuermann et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Metallothionein domain superfamily | Metallothionein domain superfamily, vertebrate | Metallothionein, vertebrate |
|---|---|---|---|---|---|
| UniProtKB:A0A0R4IE87 | InterPro | 63 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-97O18 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001201469 (1) | 368 nt | ||
| Genomic | GenBank:CR352249 (1) | 180142 nt | ||
| Polypeptide | UniProtKB:A0A0R4IE87 (1) | 63 aa |
- Dong, N., Bandura, J., Zhang, Z., Wang, Y., Labadie, K., Noel, B., Davison, A., Koene, J.M., Sun, H.S., Coutellec, M.A., Feng, Z.P. (2021) Ion channel profiling of the Lymnaea stagnalis ganglia via transcriptome analysis. BMC Genomics. 22:18
- Wang, F., Zheng, F., Liu, F. (2019) Effects of triclosan on antioxidant- and apoptosis-related genes expression in the gill and ovary of zebrafish. Experimental animals. 69(2):199-206
- Carmona-Antoñanzas, G., Santi, M., Migaud, H., Vera, L.M. (2017) Light- and clock-control of genes involved in detoxification. Chronobiology International. 34(8):1026-1041
- Wu, S.M., Shu, L.H., Liu, J.H., Chen, C.H. (2017) Anti-oxidative Responses on Hepatic Tissue of Zebrafish (Danio rerio) in a Short Duration of Sub-lethal Concentrations of Cadmium Exposure. Bulletin of environmental contamination and toxicology. 98(5):612-618
- Wu, S.M., Shu, L.H., Liu, J.H. (2016) Anti-oxidative functions of mt2 and smtB mRNA expression in the gills and brain of zebrafish (Danio rerio) upon cadmium exposure. Fish physiology and biochemistry. 42(6):1709-1720
- Schuermann, A., Helker, C.S., Herzog, W. (2015) Metallothionein 2 regulates endothelial cell migration through transcriptional regulation of vegfc expression. Angiogenesis. 18(4):463-75
- Teoh, S.L., Ogawa, S., Parhar, I.S. (2015) Localization of Genes Encoding Metallothionein-like Protein (mt2 and smtb) in the Brain of Zebrafish. Journal of chemical neuroanatomy. 70:20-32
- Wu, S.M., Liu, J.H., Shu, L.H., Chen, C.H. (2015) Anti-oxidative responses of zebrafish (Danio rerio) gill, liver and brain tissues upon acute cold shock. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 187:202-13
- Wu, S.M., Tsai, P.R., and Yan, C.J. (2012) Maternal cadmium exposure induces mt2 and smtB mRNA expression in zebrafish (Danio rerio) females and their offspring. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 156(1):1-6
- Long, Y., Li, Q., Wang, Y., and Cui, Z. (2011) MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 153(3):310-317
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