Gene
ppm1ka
- ID
- ZDB-GENE-110411-37
- Name
- protein phosphatase, Mg2+/Mn2+ dependent 1Ka
- Symbol
- ppm1ka Nomenclature History
- Previous Names
-
- si:ch211-149b19.3
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in protein dephosphorylation. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human PPM1K (protein phosphatase, Mg2+/Mn2+ dependent 1K).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| maple syrup urine disease | Alliance | ?Maple syrup urine disease, mild variant | 615135 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PPM-type phosphatase, divalent cation binding | PPM-type phosphatase-like domain | PPM-type phosphatase-like domain superfamily | Protein phosphatase 2C |
|---|---|---|---|---|---|
|
UniProtKB:E7FAZ1
|
358 | ||||
|
UniProtKB:A0A8M3B6G2
|
370 | ||||
|
UniProtKB:A0A8M9P5N7
|
290 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| aberrant processed transcript |
si:ch211-149b19.3-203
(1)
|
Havana | 1592 nt | |
| mRNA |
si:ch211-149b19.3-202
(1)
|
Havana | 1392 nt |
Interactions and Pathways
No data available
Plasmids
No data available