Gene
gckr
- ID
- ZDB-GENE-110411-248
- Name
- glucokinase (hexokinase 4) regulator
- Symbol
- gckr Nomenclature History
- Previous Names
-
- si:ch73-340m8.1
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have several functions, including carbohydrate binding activity; enzyme inhibitor activity; and fructose-6-phosphate binding activity. Involved in endocrine pancreas development; glucose homeostasis; and pancreas regeneration. Predicted to localize to cytosol; mitochondrion; and nucleoplasm. Human ortholog(s) of this gene implicated in end stage renal failure and type 2 diabetes mellitus. Orthologous to human GCKR (glucokinase regulator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from O'Hare et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from O'Hare et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Fasting plasma glucose level QTL 5] | 613463 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available