Gene

tgm5l

ID

ZDB-GENE-110411-176

Name

transglutaminase 5, like

Symbol

tgm5l Nomenclature History

Previous Names

TG-84 (1)
si:ch1073-277p6.1

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking. Human ortholog(s) of this gene implicated in hereditary spherocytosis; hereditary spherocytosis type 5; peeling skin syndrome; and spinocerebellar ataxia type 35. Orthologous to several human genes including TGM3 (transglutaminase 3); TGM5 (transglutaminase 5); and TGM6 (transglutaminase 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tgm5l Human Ortholog

No data available

Associated With tgm5l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001102	Transglutaminase, N-terminal
Domain	IPR002931	Transglutaminase-like
Domain	IPR008958	Transglutaminase, C-terminal
Family	IPR023608	Protein-glutamine gamma-glutamyltransferase, animal
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Homologous_superfamily	IPR036238	Transglutaminase, C-terminal domain superfamily
Homologous_superfamily	IPR036985	Transglutaminase-like superfamily
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily