Gene
man2a2
- ID
- ZDB-GENE-110331-1
- Name
- mannosidase, alpha, class 2A, member 2
- Symbol
- man2a2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have alpha-mannosidase activity. Predicted to be involved in N-glycan processing; mannose metabolic process; and protein deglycosylation. Predicted to localize to Golgi membrane. Orthologous to human MAN2A2 (mannosidase alpha class 2A member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Thyme et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| schizophrenia | man2a2a298/a298 | standard conditions | Thyme et al., 2019 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000602 | Glycoside hydrolase family 38, N-terminal domain |
| Domain | IPR011682 | Glycosyl hydrolase family 38, C-terminal |
| Domain | IPR015341 | Glycoside hydrolase family 38, central domain |
| Homologous_superfamily | IPR011013 | Galactose mutarotase-like domain superfamily |
| Homologous_superfamily | IPR011330 | Glycoside hydrolase/deacetylase, beta/alpha-barrel |
| Homologous_superfamily | IPR013780 | Glycosyl hydrolase, all-beta |
| Homologous_superfamily | IPR027291 | Glycoside hydrolase 38, N-terminal domain superfamily |
| Homologous_superfamily | IPR028995 | Glycoside hydrolase families 57/38, central domain superfamily |
| Homologous_superfamily | IPR037094 | Glycoside hydrolase family 38, central domain superfamily |
Domain Details Per Protein
| Protein | Length | Galactose mutarotase-like domain superfamily | Glycoside hydrolase 38, N-terminal domain superfamily | Glycoside hydrolase/deacetylase, beta/alpha-barrel | Glycoside hydrolase families 57/38, central domain superfamily | Glycoside hydrolase family 38, central domain | Glycoside hydrolase family 38, central domain superfamily | Glycoside hydrolase family 38, N-terminal domain | Glycosyl hydrolase, all-beta | Glycosyl hydrolase family 38, C-terminal |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7EYL2
|
1151 | |||||||||
|
UniProtKB:A0A8M3B6Z4
|
1167 | |||||||||
|
UniProtKB:A0A8M3AWC8
|
1174 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
man2a2-201
(1)
|
Havana | 7815 nt |
Interactions and Pathways
No data available
Plasmids
No data available