Gene
abcc6b.2
- ID
- ZDB-GENE-110208-2
- Name
- ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2
- Symbol
- abcc6b.2 Nomenclature History
- Previous Names
-
- abcc6c
- zmp:0000001324
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; ATPase activity; and ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in arterial calcification of infancy; coronary artery disease; and pseudoxanthoma elasticum. Orthologous to human ABCC6 (ATP binding cassette subfamily C member 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Li et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Li et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| arterial calcification of infancy | Alliance | Arterial calcification, generalized, of infancy, 2 | 614473 |
| pseudoxanthoma elasticum | Alliance | Pseudoxanthoma elasticum | 264800 |
| pseudoxanthoma elasticum | Alliance | Pseudoxanthoma elasticum, forme fruste | 177850 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR011527 | ABC transporter type 1, transmembrane domain |
| Family | IPR005292 | Multi drug resistance-associated protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ABC transporter type 1, transmembrane domain | ABC transporter type 1, transmembrane domain superfamily | Multi drug resistance-associated protein | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A140LGU2
|
1502 | |||||||
|
UniProtKB:A0A8M6YXP8
|
1502 | |||||||
|
UniProtKB:A0A8M9PZJ9
|
829 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
abcc6b.2-202
(1)
|
Havana | 4934 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance