ZFIN is now using GRCz12tu for Genomic Data

Gene

agbl1

ID

ZDB-GENE-110207-1

Name

AGBL carboxypeptidase 1

Symbol

agbl1 Nomenclature History

Previous Names

ccp4 (1)
cytosolic carboxypeptidase 4 (1)
si:ch73-141f14.1

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable metallocarboxypeptidase activity and tubulin binding activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol. Predicted to be active in cytoplasm and microtubule cytoskeleton.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With agbl1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Fuchs' endothelial dystrophy	Alliance	Corneal dystrophy, Fuchs endothelial, 8	615523

Associated With agbl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000834	Peptidase M14, carboxypeptidase A
Domain	IPR040626	Cytosolic carboxypeptidase, N-terminal
Family	IPR050821	Cytosolic carboxypeptidase
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0AB32TJC2	InterPro	1074
UniProtKB:A0AB32TL44	InterPro	1120
UniProtKB:A0A8M6YW35	InterPro	1105
UniProtKB:A0AC58IXK7	InterPro	1190
UniProtKB:A0AC58IXK8	InterPro	1199
UniProtKB:A0AC58IXL0	InterPro	1247
UniProtKB:A0AC58IXL4	InterPro	1174
UniProtKB:A0AC58IXL5	InterPro	1193
UniProtKB:A0AC58IXL8	InterPro	1095
UniProtKB:A0AC58IXL9	InterPro	1168
UniProtKB:A0AC58IXM1	InterPro	1134
UniProtKB:A0AC58IXM2	InterPro	1165
UniProtKB:A0AC58IXM3	InterPro	1074
UniProtKB:A0AC58IXM4	InterPro	1120
UniProtKB:A0AC58IXM5	InterPro	1101
UniProtKB:A0AC58IXM6	InterPro	1149
UniProtKB:A0AC58IXM7	InterPro	1120
UniProtKB:A0AC58IXM8	InterPro	856
UniProtKB:A0AC58IXM9	InterPro	1074
UniProtKB:A0AC58IXN0	InterPro	1074
UniProtKB:A0AC58IXN1	InterPro	1086
UniProtKB:A0AC58IXN2	InterPro	1117
UniProtKB:A0AC58IXN3	InterPro	1074
UniProtKB:A0AC58IXN4	InterPro	846
UniProtKB:A0AC58IXN5	InterPro	1026
UniProtKB:A0AC58IXN6	InterPro	1001
UniProtKB:A0AC58IXN7	InterPro	1026
UniProtKB:A0AC58IXN8	InterPro	991
UniProtKB:A0AC58IXN9	InterPro	871
UniProtKB:A0AC58IXP0	InterPro	846
UniProtKB:A0AC58IXP1	InterPro	1120
UniProtKB:A0AC58IXP2	InterPro	1057
UniProtKB:A0AC58IXP3	InterPro	821
UniProtKB:A0AC58IXP4	InterPro	821
UniProtKB:A0AC58IXP6	InterPro	1026
UniProtKB:A0AC58IXP7	InterPro	796
UniProtKB:A0AC58IXP8	InterPro	874
UniProtKB:A0AC58IXP9	InterPro	892
UniProtKB:A0AC58IXQ0	InterPro	796
UniProtKB:A0AC58IXQ2	InterPro	796
UniProtKB:A0AC58IXQ4	InterPro	881
UniProtKB:A0AC58IXQ7	InterPro	821
UniProtKB:A0AC58IXQ8	InterPro	796

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	agbl1-201 (1) Ensembl	Ensembl	1,457 nt	Select Tool ZFIN BLAST
mRNA	agbl1-202 (1) Ensembl	Ensembl	6,462 nt	Select Tool ZFIN BLAST
mRNA	agbl1-203 (1) Ensembl	Ensembl	6,383 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations