Gene

bicc2

ID

ZDB-GENE-110110-3

Name

bicaudal C homolog 2

Symbol

bicc2 Nomenclature History

Previous Names

bicc1a (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Used to study autosomal dominant polycystic kidney disease. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Orthologous to human BICC1 (BicC family RNA binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Bouvrette et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Bouvrette et al., 2010
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bicc2 Human Ortholog

No data available

Associated With bicc2 Via Experimental Models

Human Disease	Fish	Conditions	Citations
autosomal dominant polycystic kidney disease	WT + MO1-bicc2	standard conditions	Bouvrette et al., 2010

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR004087	K Homology domain
Domain	IPR004088	K Homology domain, type 1
Domain	IPR037974	BICC1, SAM domain
Domain	IPR047549	BICC1, first type I KH domain
Domain	IPR047553	BICC1, third type I KH domain
Domain	IPR047554	BICC1, second type I KH
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR036612	K Homology domain, type 1 superfamily