Gene
bicc2
- ID
- ZDB-GENE-110110-3
- Name
- bicaudal C homolog 2
- Symbol
- bicc2 Nomenclature History
- Previous Names
-
- bicc1a (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to be active in cytoplasm. Used to study autosomal dominant polycystic kidney disease.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bouvrette et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Bouvrette et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Targeting Reagent | Created Alleles | Citations |
---|---|---|
MO1-bicc2 | N/A | Bouvrette et al., 2010 |
MO2-bicc2 | N/A | Bouvrette et al., 2010 |
1 - 2 of 2
Show
Human Disease
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
autosomal dominant polycystic kidney disease | WT + MO1-bicc2 | standard conditions | Bouvrette et al., 2010 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | BICC1, first type I KH domain | BICC1, SAM domain | BICC1, second type I KH | BICC1, third type I KH domain | K Homology domain | K Homology domain, type 1 | K Homology domain, type 1 superfamily | Protein bicaudal C homolog 1, KH-like domain | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q6R5A4 | InterPro | 846 | ||||||||||
UniProtKB:A0AB32T2A4 | InterPro | 889 | ||||||||||
UniProtKB:A0AB32T2M1 | InterPro | 799 |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-201I24 | ZFIN Curated Data |
1 - 1 of 1
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_203420 (1) | 2997 nt | ||
Genomic | GenBank:CU468924 (2) | 159932 nt | ||
Polypeptide | UniProtKB:A0AB32T2A4 (1) | 889 aa |
No data available
- Choksi, S.P., Babu, D., Lau, D., Yu, X., Roy, S. (2014) Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development (Cambridge, England). 141:3410-9
- Amemiya, C.T., Alfoldi, J., Lee, A.P., Fan, S., Philippe, H., MacCallum, I., Braasch, I., Manousaki, T., Schneider, I., Rohner, N., Organ, C., Chalopin, D., Smith, J.J., Robinson, M., Dorrington, R.A., Gerdol, M., Aken, B., Biscotti, M.A., Barucca, M., Baurain, D., Berlin, A.M., Blatch, G.L., Buonocore, F., Burmester, T., Campbell, M.S., Canapa, A., Cannon, J.P., Christoffels, A., de Moro, G., Edkins, A.L., Fan, L., Fausto, A.M., Feiner, N., Forconi, M., Gamieldien, J., Gnerre, S., Gnirke, A., Goldstone, J.V., Haerty, W., Hahn, M.E., Hesse, U., Hoffmann, S., Johnson, J., Karchner, S.I., Karaku, S., Lara, M., Levin, J.Z., Litman, G.W., Mauceli, E., Miyake, T., Mueller, M.G., Nelson, D.R., Nitsche, A., Olmo, E., Ota, T., Pallavicini, A., Panji, S., Picone, B., Ponting, C.P., Prohaska, S.J., Przybylski, D., Saha, N.R., Ravi, V., Ribeiro, F.J., Sauka-Spengler, T., Scapigliati, G., Searle, S.M.J., Sharpe, T., Simakov, O., Stadler, P.F., Stegeman, J.J., Sumiyama, K., Tabbaa, D., Tafer, H., Turner-Maier, J., van Heusden, P., White, S., Williams, L., Yandell, M., Brinkmann, H., Volff, J.N., Tabin, C.J., Shubin, N., Schartl, M., Jaffe, D.B., Postlethwait, J.H., Venkatesh, B., Palma, F.D., Lander, E.S., Meyer, A., and Lindblad-Toh, K. (2013) The African coelacanth genome provides insights into tetrapod evolution. Nature. 496:311-316
- Bouvrette, D.J., Sittaramane, V., Heidel, J.R., Chandrasekhar, A., and Bryda, E.C. (2010) Knockdown of bicaudal C in zebrafish (Danio rerio) causes cystic kidneys: a nonmammalian model of polycystic kidney disease. Comparative medicine. 60(2):96-106
1 - 3 of 3
Show