ZFIN is now using GRCz12tu for Genomic Data
Gene
mical2a
- ID
- ZDB-GENE-110110-2
- Name
- microtubule associated monooxygenase, calponin and LIM domain containing 2a
- Symbol
- mical2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable actin binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be involved in actin filament depolymerization. Predicted to be located in cytoplasm and nucleus. Is expressed in fin; heart; heart tube; and pharyngeal arch. Orthologous to human MICAL2 (microtubule associated monooxygenase, calponin and LIM domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xue et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR001781 | Zinc finger, LIM-type |
| Domain | IPR002938 | FAD-binding domain |
| Domain | IPR057494 | [F-actin]-monooxygenase MICAL1-3-like, Rossman domain |
| Family | IPR050540 | F-actin Monooxygenase Mical |
| Homologous_superfamily | IPR036188 | FAD/NAD(P)-binding domain superfamily |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mical2a-201
(1)
|
Ensembl | 3,980 nt | ||
| mRNA |
mical2a-202
(1)
|
Ensembl | 2,505 nt | ||
| mRNA |
mical2a-203
(1)
|
Ensembl | 1,896 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers