Gene
grin2db
- ID
- ZDB-GENE-100920-7
- Name
- glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
- Symbol
- grin2db Nomenclature History
- Previous Names
-
- NR2D.1 (1)
- si:dkey-209f7.2
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable NMDA glutamate receptor activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in organelle and postsynaptic membrane. Predicted to be part of NMDA selective glutamate receptor complex. Is expressed in forebrain; hindbrain; midbrain; presumptive neural retina; and spinal cord.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 46 | Alliance | Developmental and epileptic encephalopathy 46 | 617162 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001320 | Ionotropic glutamate receptor, C-terminal |
| Domain | IPR019594 | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
| Family | IPR001508 | Ionotropic glutamate receptor, metazoa |
| Family | IPR015683 | Ionotropic glutamate receptor |
| Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ionotropic glutamate receptor | Ionotropic glutamate receptor, C-terminal | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain | Ionotropic glutamate receptor, metazoa | Periplasmic binding protein-like I |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AT83 | InterPro | 1959 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
grin2db-202
(1)
|
Ensembl | 3,303 nt |
Interactions and Pathways
No data available
Plasmids
No data available