Gene
ppip5k1a
- ID
- ZDB-GENE-100426-4
- Name
- diphosphoinositol pentakisphosphate kinase 1a
- Symbol
- ppip5k1a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable 5-diphosphoinositol pentakisphosphate 1-kinase activity and inositol hexakisphosphate kinase activity. Predicted to be involved in inositol phosphate biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol. Orthologous to human PPIP5K1 (diphosphoinositol pentakisphosphate kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa2349 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa8681 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa10406 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa16976 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa18089 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa18894 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa21076 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa21077 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa21078 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa30893 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR033379 | Histidine acid phosphatase active site |
Domain | IPR040557 | VIP1, N-terminal |
Family | IPR000560 | Histidine phosphatase superfamily, clade-2 |
Family | IPR037446 | Histidine acid phosphatase, VIP1 family |
Homologous_superfamily | IPR029033 | Histidine phosphatase superfamily |
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Domain Details Per Protein
Protein | Additional Resources | Length | Histidine acid phosphatase active site | Histidine acid phosphatase, VIP1 family | Histidine phosphatase superfamily | Histidine phosphatase superfamily, clade-2 | VIP1, N-terminal |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QD12 | InterPro | 1404 | |||||
UniProtKB:A0A8M9QI11 | InterPro | 1282 | |||||
UniProtKB:A0A8N7UVM3 | InterPro | 1324 | |||||
UniProtKB:A0A8M9Q2S4 | InterPro | 1362 | |||||
UniProtKB:A0A8M9Q8X0 | InterPro | 1342 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
ppip5k1a-201
(1)
|
Ensembl | 7,683 nt | ||
mRNA |
ppip5k1a-202
(1)
|
Ensembl | 4,038 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-44A21 | ZFIN Curated Data | |
Contained in | BAC | CH211-258F15 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_068222730 (1) | 6143 nt | ||
Genomic | GenBank:AL928670 (2) | 167613 nt | ||
Polypeptide | UniProtKB:A0AB32TTL5 (1) | 1405 aa |
- Comparative Orthology
- Alliance
- Zhao, Y., Yang, G., Wu, N., Cao, X., Gao, J. (2020) Integrated transcriptome and phosphoproteome analyses reveal that fads2 is critical for maintaining body LC-PUFA homeostasis. Journal of proteomics. 229:103967
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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