ZFIN is now using GRCz12tu for Genomic Data
Gene
brsk2b
- ID
- ZDB-GENE-100422-3
- Name
- BR serine/threonine kinase 2b
- Symbol
- brsk2b Nomenclature History
- Previous Names
-
- zmp:0000000828
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable tau-protein kinase activity. Acts upstream of or within social behavior; swimming behavior; and thigmotaxis. Predicted to be active in centrosome. Is expressed in brain. Orthologous to human BRSK2 (BR serine/threonine kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Deng et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| autism spectrum disorder | brsk2bzf3706/zf3706 (TU) | standard conditions | Deng et al., 2022 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | BRSK1/2-like, UBA domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B1F0 | InterPro | 886 | |||||
| UniProtKB:A0A8M3AUI3 | InterPro | 881 | |||||
| UniProtKB:A0A8M3AUH0 | InterPro | 827 | |||||
| UniProtKB:A0A8M3BB82 | InterPro | 863 | |||||
| UniProtKB:A0A8M6Z088 | InterPro | 736 | |||||
| UniProtKB:A0A8M9PQ27 | InterPro | 822 | |||||
| UniProtKB:A0A8M1QHP3 | InterPro | 713 | |||||
| UniProtKB:A0AB32TW61 | InterPro | 804 | |||||
| UniProtKB:A0AC58G0U4 | InterPro | 731 | |||||
| UniProtKB:A0AC58G0U5 | InterPro | 672 | |||||
| UniProtKB:A0AC58G0V1 | InterPro | 667 | |||||
| UniProtKB:A0AC58G0V2 | InterPro | 799 | |||||
| UniProtKB:A0AC58G0V3 | InterPro | 672 | |||||
| UniProtKB:A0AC58G0V5 | InterPro | 654 | |||||
| UniProtKB:A0AC58G0V6 | InterPro | 672 | |||||
| UniProtKB:A0AC58G0V7 | InterPro | 804 | |||||
| UniProtKB:A0AC58G0V8 | InterPro | 822 | |||||
| UniProtKB:A0AC58G0Y5 | InterPro | 677 | |||||
| UniProtKB:A0AC58G0Y8 | InterPro | 677 | |||||
| UniProtKB:A0AC58G106 | InterPro | 654 | |||||
| UniProtKB:A0AC58G140 | InterPro | 822 | |||||
| UniProtKB:A0AC58G150 | InterPro | 649 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
brsk2b-201
(1)
|
Ensembl | 2,278 nt | ||
| mRNA |
brsk2b-202
(1)
|
Ensembl | 318 nt | ||
| mRNA |
brsk2b-203
(1)
|
Ensembl | 4,281 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance