ZFIN is now using GRCz12tu for Genomic Data
Gene

ppfia3

ID
ZDB-GENE-100311-3
Name
PTPRF interacting protein alpha 3
Symbol
ppfia3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Acts upstream of or within vasculature development. Predicted to be located in cytoplasm. Predicted to be active in presynaptic active zone. Orthologous to human PPFIA3 (PPFI scaffold protein A3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Mana et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppfia3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Paul-Chao neurodevelopmental syndrome 621122
Associated With ppfia3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001660 Sterile alpha motif domain
Domain IPR037620 Liprin-alpha, SAM domain 1
Domain IPR037621 Liprin-alpha, SAM domain 2
Domain IPR037622 Liprin-alpha, SAM domain 3
Domain IPR057892 Liprin-alpha, CC2 domain
Family IPR029515 Liprin
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Liprin Liprin-alpha, CC2 domain Liprin-alpha, SAM domain 1 Liprin-alpha, SAM domain 2 Liprin-alpha, SAM domain 3 Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily
UniProtKB:X1WCJ5 InterPro 1226
UniProtKB:A0A8M9Q8T7 InterPro 1206
UniProtKB:A0AC58J2D1 InterPro 1206
UniProtKB:A0AC58J2D5 InterPro 1226
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ppfia3-201 (1)
Ensembl
Ensembl 1,845 nt
ZFIN BLAST
mRNA ppfia3-202 (1)
Ensembl
Ensembl 4,778 nt
ZFIN BLAST
mRNA ppfia3-203 (1)
Ensembl
Ensembl 741 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Citations
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