Gene
mmp19
- ID
- ZDB-GENE-100308-3
- Name
- matrix metallopeptidase 19
- Symbol
- mmp19 Nomenclature History
- Previous Names
-
- zmp:0000001022 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable metalloendopeptidase activity and zinc ion binding activity. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular matrix. Orthologous to human MMP19 (matrix metallopeptidase 19).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa10035 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Cavitary optic disc anomalies | 611543 |
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Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Hemopexin, conserved site | Hemopexin-like domain | Hemopexin-like domain superfamily | Hemopexin-like repeats | Metallopeptidase, catalytic domain superfamily | Peptidase M10A | Peptidase M10A, catalytic domain | Peptidase M10, metallopeptidase | Peptidase, metallopeptidase | Peptidoglycan binding-like | PGBD-like superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0AB32TZ88 | InterPro | 478 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-290L19 | ZFIN Curated Data | |
Contained in | Fosmid | CH1073-182B19 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_068224261 (1) | 1821 nt | ||
Genomic | GenBank:CU633767 (1) | 38548 nt | ||
Polypeptide | UniProtKB:A0AB32TZ88 (1) | 478 aa |
- Comparative Orthology
- Alliance
- Tsarouchas, T.M., Wehner, D., Cavone, L., Munir, T., Keatinge, M., Lambertus, M., Underhill, A., Barrett, T., Kassapis, E., Ogryzko, N., Feng, Y., van Ham, T.J., Becker, T., Becker, C.G. (2018) Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration. Nature communications. 9:4670
- Wyatt, R.A., Keow, J.Y., Harris, N.D., Haché, C.A., Li, D.H., and Crawford, B.D. (2009) The Zebrafish Embryo: A Powerful Model System for Investigating Matrix Remodeling. Zebrafish. 6(4):347-354
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