ZFIN is now using GRCz12tu for Genomic Data
Gene

col27a1a

ID
ZDB-GENE-100119-1
Name
collagen, type XXVII, alpha 1a
Symbol
col27a1a Nomenclature History
Previous Names
  • cb221 (1)
  • sb:cb221
Type
protein_coding_gene
Location
Ambiguous Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Acts upstream of or within bone mineralization; notochord morphogenesis; and skeletal system development. Predicted to be active in extracellular matrix. Is expressed in several structures, including hypochord; mesoderm; periderm; pronephric duct; and skeletal system. Orthologous to human COL27A1 (collagen type XXVII alpha 1 chain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Christiansen et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la019844TgTransgenic insertionUnknownUnknownDNA
la019845TgTransgenic insertionUnknownUnknownDNA
la027783TgTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-col27a1aN/AChristiansen et al., 2009
MO2-col27a1aN/AChristiansen et al., 2009
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Human Disease
Associated With col27a1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Steel syndrome 615155
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Associated With col27a1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000885 Fibrillar collagen, C-terminal
Domain IPR001791 Laminin G domain
Domain IPR048287 Thrombospondin-like, N-terminal domain
Family IPR050938 Collagen and Collagen-like Structural Proteins
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length Collagen and Collagen-like Structural Proteins Collagen triple helix repeat Concanavalin A-like lectin/glucanase domain superfamily Fibrillar collagen, C-terminal Laminin G domain Thrombospondin-like, N-terminal domain
UniProtKB:C7DZK3 InterPro 1783
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Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
EncodesESTcb221Mangos et al., 2010
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Sequences
Genome Browsers
Genome Assembly: GRCz12tuChromosome: 21
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanCOL27A19
Amino acid sequence comparison (1)
MouseCol27a14
Amino acid sequence comparison (1)
Citations
1 - 10 of 11
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