Gene

tmprss15

ID
ZDB-GENE-091204-83
Name
transmembrane serine protease 15
Symbol
tmprss15 Nomenclature History
Previous Names
  • si:dkeyp-23e4.2
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have scavenger receptor activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to membrane. Human ortholog(s) of this gene implicated in enterokinase deficiency. Orthologous to human TMPRSS15 (transmembrane serine protease 15).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tmprss15 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
enterokinase deficiency Alliance Enterokinase deficiency 226200
Associated With tmprss15 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Conserved_site IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
Domain IPR000082 SEA domain
Domain IPR000859 CUB domain
Domain IPR000998 MAM domain
Domain IPR001190 SRCR domain
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR017448 SRCR-like domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR035914 Spermadhesin, CUB domain superfamily
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Homologous_superfamily IPR036364 SEA domain superfamily
Homologous_superfamily IPR036772 SRCR-like domain superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily CUB domain LDL receptor-like superfamily Low-density lipoprotein (LDL) receptor class A, conserved site Low-density lipoprotein (LDL) receptor class A repeat MAM domain Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold SEA domain SEA domain superfamily Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Serine proteases, trypsin family, serine active site Spermadhesin, CUB domain superfamily SRCR domain SRCR-like domain SRCR-like domain superfamily
UniProtKB:A0A8M9PWC3 990
UniProtKB:F1RER3 990
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations