Gene
tmtops3b
- ID
- ZDB-GENE-091204-311
- Name
- teleost multiple tissue opsin 3b
- Symbol
- tmtops3b Nomenclature History
- Previous Names
-
- tmt2a (1)
- si:ch73-52f15.6
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to act upstream of or within signal transduction and visual perception. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in several structures, including endocrine system; eye; gill; heart; and integument.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Davies et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G-protein coupled receptor opsins | G protein-coupled receptor, rhodopsin-like | Peropsin | Visual pigments (opsins) retinal binding site |
|---|---|---|---|---|---|---|---|
| UniProtKB:R9R6D4 | InterPro | 379 | |||||
| UniProtKB:A0A0N9NKH0 | InterPro | 357 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmtops3b-201
(1)
|
Ensembl | 1,074 nt | ||
| mRNA |
tmtops3b-202
(1)
|
Ensembl | 613 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-52F15 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001282375 (1) | 1140 nt | ||
| Genomic | GenBank:CU468967 (2) | 131614 nt | ||
| Polypeptide | UniProtKB:R9R6D4 (1) | 379 aa |
No data available
- Liang, Q., Afriyie, G., Chen, Z., Xu, Z., Dong, Z., Wang, Z., Guo, Y. (2021) Analysis of Opsin Gene Family of Crimson Snapper (Lutjanus erythropterus). Gene. 807:145960
- Steindal, I.A.F., Whitmore, D. (2020) Zebrafish Circadian Clock Entrainment and the Importance of Broad Spectral Light Sensitivity. Frontiers in Physiology. 11:1002
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Davies, W.I., Tamai, T.K., Zheng, L., Fu, J.K., Rihel, J., Foster, R.G., Whitmore, D., Hankins, M.W. (2015) An extended family of novel vertebrate photopigments is widely expressed and displays a diversity of function. Genome research. 25(11):1666-79
- Jiang, L., Romero-Carvajal, A., Haug, J.S., Seidel, C.W., Piotrowski, T. (2014) Gene-expression analysis of hair cell regeneration in the zebrafish lateral line. Proceedings of the National Academy of Sciences of the United States of America. 111:E1383-92
- Fischer, R.M., Fontinha, B.M., Kirchmaier, S., Steger, J., Bloch, S., Inoue, D., Panda, S., Rumpel, S., and Tessmar-Raible, K. (2013) Co-Expression of VAL- and TMT-Opsins Uncovers Ancient Photosensory Interneurons and Motorneurons in the Vertebrate Brain. PLoS Biology. 11(6):e1001585
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