Gene
gdpd5a
- ID
- ZDB-GENE-091204-253
- Name
- glycerophosphodiester phosphodiesterase domain containing 5a
- Symbol
- gdpd5a Nomenclature History
- Previous Names
-
- fk20b05
- si:ch211-30e10.2
- wu:fk20b05
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable glycerophosphodiester phosphodiesterase activity. Acts upstream of or within hatching and swimming behavior. Located in plasma membrane. Orthologous to human GDPD5 (glycerophosphodiester phosphodiesterase domain containing 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from van Veen et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Glycerophosphodiester phosphodiesterase domain | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
---|---|---|---|---|
UniProtKB:A0A8N7T693 | InterPro | 595 | ||
UniProtKB:E7FGJ8 | InterPro | 600 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
gdpd5a-201
(1)
|
Ensembl | 5,197 nt | ||
mRNA |
gdpd5a-202
(1)
|
Ensembl | 998 nt | ||
mRNA |
gdpd5a-203
(1)
|
Ensembl | 618 nt | ||
mRNA |
gdpd5a-204
(1)
|
Ensembl | 5,284 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-30E10 | ZFIN Curated Data | |
Encodes | EST | fk20b05 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_677714 (1) | 2976 nt | ||
Genomic | GenBank:BX000451 (1) | 153155 nt | ||
Polypeptide | UniProtKB:E7FGJ8 (1) | 600 aa |
- Prendergast, A.E., Jim, K.K., Marnas, H., Desban, L., Quan, F.B., Djenoune, L., Laghi, V., Hocquemiller, A., Lunsford, E.T., Roussel, J., Keiser, L., Lejeune, F.X., Dhanasekar, M., Bardet, P.L., Levraud, J.P., van de Beek, D., Vandenbroucke-Grauls, C.M.J.E., Wyart, C. (2023) CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection. Current biology : CB. 33(5):940-956.e10
- van Veen, M., Mans, L.A., Matas-Rico, E., van Pelt, J., Perrakis, A., Moolenaar, W.H., Haramis, A.G. (2017) Glycerophosphodiesterase GDE2/GDPD5 affects pancreas differentiation in zebrafish. The international journal of biochemistry & cell biology. 94:71-78
- Yartseva, V., Takacs, C.M., Vejnar, C.E., Lee, M.T., Giraldez, A.J. (2017) RESA identifies mRNA-regulatory sequences at high resolution. Nature Methods. 14(2):201-207
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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