Gene
ccl19b
- ID
- ZDB-GENE-091204-19
- Name
- chemokine (C-C motif) ligand 19b
- Symbol
- ccl19b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable chemokine activity. Predicted to act upstream of or within immune response. Predicted to be located in extracellular space. Orthologous to human CCL19 (C-C motif chemokine ligand 19).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Nomiyama et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa5828 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily |
---|---|---|---|---|---|
UniProtKB:A0A8M1P631 | InterPro | 114 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
ccl19b-201
(1)
|
Ensembl | 743 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-200L5 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001302701 (1) | |||
Genomic | GenBank:CR925808 (1) | 170902 nt | ||
Polypeptide | UniProtKB:A0A8M1P631 (1) | 114 aa |
- Mi, X., Song, Y., Deng, C., Yan, J., Li, Z., Li, Y., Zheng, J., Yang, W., Gong, L., Shi, J. (2023) Stimulation of liver fibrosis by N2 neutrophils in Wilson's disease. Cellular and molecular gastroenterology and hepatology. 16(5):657-684
- Zhu, H., Wang, Z., Wang, W., Lu, Y., He, Y.W., Tian, J. (2022) Bacterial Quorum-Sensing Signal DSF Inhibits LPS-Induced Inflammations by Suppressing Toll-like Receptor Signaling and Preventing Lysosome-Mediated Apoptosis in Zebrafish. International Journal of Molecular Sciences. 23(13)
- Yu, L., Li, C.H., Chen, J. (2019) A novel CC chemokine ligand 2 like gene from ayu Plecoglossus altivelis is involved in the innate immune response against to Vibrio anguillarum. Fish & shellfish immunology. 87:886-896
- Zhou, T., Li, N., Jin, Y., Zeng, Q., Prabowo, W., Liu, Y., Tian, C., Bao, L., Liu, S., Yuan, Z., Fu, Q., Gao, S., Gao, D., Dunham, R., Shubin, N.H., Liu, Z. (2018) Chemokine C-C motif ligand 33 is a key regulator of teleost fish barbel development. Proceedings of the National Academy of Sciences of the United States of America. 115(22):E5018-E5027
- Xue, Y., Lv, J., Zhang, C., Wang, L., Ma, D., Liu, F. (2017) The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b. Developmental Cell. 42(4):349-362.e4
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Nomiyama, H., Osada, N., and Yoshie, O. (2013) Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history. Genes to cells : devoted to molecular & cellular mechanisms. 18(1):1-16
- Nomiyama, H., Hieshima, K., Osada, N., Kato-Unoki, Y., Otsuka-Ono, K., Takegawa, S., Izawa, T., Yoshizawa, A., Kikuchi, Y., Tanase, S., Miura, R., Kusuda, J., Nakao, M., and Yoshie, O. (2008) Extensive Expansion and Diversification of the Chemokine Gene Family in Zebrafish: Identification of a Novel Chemokine Subfamily CX. BMC Genomics. 9(1):222
- Peatman, E., and Liu, Z. (2006) CC chemokines in zebrafish: Evidence for extensive intrachromosomal gene duplications. Genomics. 88(3):381-385
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