Gene
cetn2
- ID
- ZDB-GENE-091118-94
- Name
- centrin, EF-hand protein, 2
- Symbol
- cetn2 Nomenclature History
- Previous Names
-
- si:dkey-169h1.9
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in centriole replication. Predicted to be located in microtubule organizing center. Predicted to be active in centriole; centrosome; and nucleus. Is expressed in pronephros. Orthologous to human CETN2 (centrin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa38986 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Conserved_site | IPR000629 | ATP-dependent RNA helicase DEAD-box, conserved site |
| Domain | IPR002048 | EF-hand domain |
| Family | IPR050230 | Calmodulin/Myosin light chain/Troponin C-like |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
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Domain Details Per Protein
| Protein | Additional Resources | Length | ATP-dependent RNA helicase DEAD-box, conserved site | Calmodulin/Myosin light chain/Troponin C-like | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IVN1 | InterPro | 172 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-169H1 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001345030 (1) | |||
| Genomic | GenBank:CR753843 (1) | 112358 nt | ||
| Polypeptide | UniProtKB:A0A0R4IVN1 (1) | 172 aa |
- Ercanbrack, W.S., Dungan, A., Gaul, E., Ramirez, M., J DelVecchio, A., Grass, C., Wingert, R.A. (2024) Frataxin is essential for zebrafish embryogenesis and pronephros formation. Frontiers in cell and developmental biology. 12:14962441496244
- Jaffe, K.M., Grimes, D.T., Schottenfeld-Roames, J., Werner, M.E., Ku, T.J., Kim, S.K., Pelliccia, J.L., Morante, N.F., Mitchell, B.J., Burdine, R.D. (2016) c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Reports. 14(8):1841-9
- Andersen, E.F., and Halloran, M.C. (2012) Centrosome movements in vivo correlate with specific neurite formation downstream of LIM homeodomain transcription factor activity. Development (Cambridge, England). 139(19):3590-3599
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