Gene

erap1a

ID
ZDB-GENE-091113-7
Name
endoplasmic reticulum aminopeptidase 1a
Symbol
erap1a Nomenclature History
Previous Names
  • si:dkey-24n17.6
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be active in cytoplasm; extracellular space; and membrane. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum aminopeptidase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa15064Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa41570Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With erap1a Human Ortholog
No data available
Associated With erap1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR014782 Peptidase M1, membrane alanine aminopeptidase
Domain IPR024571 ERAP1-like C-terminal domain
Domain IPR045357 Aminopeptidase N-like , N-terminal domain
Family IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Family IPR034016 Aminopeptidase N-type
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Domain Details Per Protein
Protein Additional Resources Length Aminopeptidase N-like , N-terminal domain Aminopeptidase N-like , N-terminal domain superfamliy Aminopeptidase N-type ERAP1-like C-terminal domain Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase Peptidase M1 family aminopeptidases Peptidase M1, membrane alanine aminopeptidase Peptidase M4/M1, CTD superfamily
UniProtKB:A0A8M9Q695 InterPro 918
UniProtKB:A0A8M3B5Z1 InterPro 855
UniProtKB:A0A8M2B1Z9 InterPro 932
UniProtKB:A0A8M3AWF2 InterPro 933
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 10
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA erap1a-201 (1)
Ensembl
Ensembl 3,323 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-24N17ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_005155533 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:CR394525 (1)215862 nt
MegaBLAST
PolypeptideUniProtKB:A0A8M3AWF2 (1)933 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanERAP15
Amino acid sequence comparison (1)
MouseErap113
Amino acid sequence comparison (1)
Citations
TSV
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