Gene

recql4

ID
ZDB-GENE-091112-2
Name
RecQ helicase-like 4
Symbol
recql4 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; nucleic acid binding activity; and zinc ion binding activity. Human ortholog(s) of this gene implicated in Baller-Gerold syndrome; Rothmund-Thomson syndrome; and rapadilino syndrome. Orthologous to human RECQL4 (RecQ like helicase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With recql4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Baller-Gerold syndrome Alliance Baller-Gerold syndrome 218600
rapadilino syndrome Alliance RAPADILINO syndrome 266280
Rothmund-Thomson syndrome Alliance Rothmund-Thomson syndrome, type 2 268400
Associated With recql4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001650 Helicase, C-terminal
Domain IPR001878 Zinc finger, CCHC-type
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Family IPR021110 DNA replication/checkpoint protein
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036875 Zinc finger, CCHC-type superfamily
Domain Details Per Protein
Protein Length DEAD/DEAH box helicase domain DNA replication/checkpoint protein Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase Zinc finger, CCHC-type Zinc finger, CCHC-type superfamily
UniProtKB:E7F8R0
UniProtKB:E7F2M7 1459
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations