ZFIN is now using GRCz12tu for Genomic Data

Gene

asap1b

ID

ZDB-GENE-091112-16

Name

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b

Symbol

asap1b Nomenclature History

Previous Names

asap1
si:dkey-37o8.2

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable GTPase activator activity. Predicted to be involved in cilium assembly and positive regulation of membrane tubulation. Predicted to be active in plasma membrane; podosome; and trans-Golgi network membrane. Is expressed in head. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Cui et al., 2020

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With asap1b Human Ortholog

No data available

Associated With asap1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001164	Arf GTPase activating protein
Domain	IPR001452	SH3 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR004148	BAR domain
Domain	IPR037844	ASAP, PH domain
Domain	IPR037928	ASAP1, BAR domain
Domain	IPR038016	ASAP1, SH3 domain
Family	IPR043593	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR027267	AH/BAR domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Homologous_superfamily	IPR037278	ARFGAP/RecO-like zinc finger
Homologous_superfamily	IPR038508	ArfGAP domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A2R8RMX4	InterPro	1062
UniProtKB:A0A8M3ANG5	InterPro	1133
UniProtKB:A0A8M3AZ08	InterPro	1137
UniProtKB:A0A8M3AVY1	InterPro	1136
UniProtKB:A0A8M2B9F9	InterPro	1086
UniProtKB:A0A2R8PVI8	InterPro	1082
UniProtKB:E7FGT3	InterPro	1113
UniProtKB:A0A8M2B9I0	InterPro	1109
UniProtKB:A0A8M9PM69	InterPro	1134
UniProtKB:A0AB32TFB9	InterPro	1106
UniProtKB:A0AB32TGU4	InterPro	1085
UniProtKB:A0AB32TIP6	InterPro	1085
UniProtKB:A0AC58ITZ4	InterPro	599
UniProtKB:A0AC58ITZ5	InterPro	1105
UniProtKB:A0AC58ITZ8	InterPro	1083
UniProtKB:A0AC58IU00	InterPro	1156

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	asap1b-201 (1) Ensembl	Ensembl	8,967 nt	Select Tool ZFIN BLAST
mRNA	asap1b-202 (1) Ensembl	Ensembl	1,048 nt	Select Tool ZFIN BLAST
mRNA	asap1b-204 (1) Ensembl	Ensembl	669 nt	Select Tool ZFIN BLAST
mRNA	asap1b-205 (1) Ensembl	Ensembl	4,009 nt	Select Tool ZFIN BLAST
mRNA	asap1b-206 (1) Ensembl	Ensembl	8,508 nt	Select Tool ZFIN BLAST
mRNA	asap1b-207 (1) Ensembl	Ensembl	9,036 nt	Select Tool ZFIN BLAST
mRNA	asap1b-208 (1) Ensembl	Ensembl	8,883 nt	Select Tool ZFIN BLAST
mRNA	asap1b-209 (1) Ensembl	Ensembl	8,814 nt	Select Tool ZFIN BLAST
ncRNA	asap1b-004 (1) Ensembl	Ensembl	821 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations