Gene
cep131
- ID
- ZDB-GENE-090508-16
- Name
- centrosomal protein 131
- Symbol
- cep131 Nomenclature History
- Previous Names
-
- azi1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Involved in several processes, including Kupffer's vesicle development; intraciliary retrograde transport; and melanosome transport. Acts upstream of or within cilium assembly and epithelial cilium movement involved in determination of left/right asymmetry. Predicted to be located in several cellular components, including acrosomal vesicle; chromosome, centromeric region; and cytoskeleton. Predicted to be active in centriolar satellite. Used to study Bardet-Biedl syndrome. Orthologous to human CEP131 (centrosomal protein 131).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Bardet-Biedl syndrome | WT + MO1-cep131 | standard conditions | Chamling et al., 2014 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR030465 | Centrosomal protein of 131kDa |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Centrosomal protein of 131kDa |
|---|---|---|---|
| UniProtKB:A0A8M9PB00 | InterPro | 1101 | |
| UniProtKB:A0A8M9Q419 | InterPro | 1111 | |
| UniProtKB:A0A8M3AYM7 | InterPro | 1110 | |
| UniProtKB:E7FAG4 | InterPro | 1111 | |
| UniProtKB:U3JAG9 | InterPro | 1113 |
1 - 5 of 8 Show all
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cep131-201
(1)
|
Ensembl | 8,681 nt | ||
| mRNA |
cep131-202
(1)
|
Ensembl | 3,213 nt | ||
| mRNA |
cep131-203
(1)
|
Ensembl | 3,309 nt |
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Interactions and Pathways
No data available
Plasmids
No data available