Gene
erlin2
- ID
- ZDB-GENE-090505-4
- Name
- ER lipid raft associated 2
- Symbol
- erlin2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have cholesterol binding activity. Predicted to be involved in SREBP signaling pathway. Predicted to localize to endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 18. Orthologous to human ERLIN2 (ER lipid raft associated 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907527 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 18 | Alliance | Spastic paraplegia 18B, autosomal recessive | 611225 |
| Spastic paraplegia 18A, autosomal dominant | 620512 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
ch25hl3-201
(1)
|
Havana | 3869 nt | |
| mRNA |
erlin2-201
(1)
|
Havana | 774 nt |
Interactions and Pathways
No data available
Plasmids
No data available