Gene
gprc5bb
- ID
- ZDB-GENE-090313-75
- Name
- G protein-coupled receptor, class C, group 5, member Bb
- Symbol
- gprc5bb Nomenclature History
- Previous Names
-
- si:ch211-202h22.5
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable protein kinase activator activity and protein kinase binding activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in extracellular exosome and plasma membrane. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts. Orthologous to human GPRC5B (G protein-coupled receptor class C group 5 member B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Greenhough et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Megalencephalic leukoencephalopathy with subcortical cysts 3 | 620447 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR family 3, C-terminal | Retinoic acid-inducible GPCR family 3 |
|---|---|---|---|---|
| UniProtKB:A0A8M2B722 | InterPro | 407 | ||
| UniProtKB:B8A4H2 | InterPro | 406 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gprc5bb-201
(1)
|
Ensembl | 1,314 nt | ||
| mRNA |
gprc5bb-202
(1)
|
Ensembl | 2,016 nt |
Interactions and Pathways
No data available
Plasmids
No data available