Gene
ttc3
- ID
- ZDB-GENE-090313-3
- Name
- tetratricopeptide repeat domain 3
- Symbol
- ttc3 Nomenclature History
- Previous Names
-
- si:ch1073-446e18.3
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Orthologous to human TTC3 (tetratricopeptide repeat domain 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa17296 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa21623 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa21624 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa30648 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa31756 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 5 of 5
Show
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001841 | Zinc finger, RING-type |
Domain | IPR043866 | E3 ubiquitin-protein ligase TTC3/DZIP3 domain |
Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Repeat | IPR019734 | Tetratricopeptide repeat |
1 - 5 of 5
Domain Details Per Protein
Protein | Additional Resources | Length | E3 ubiquitin-protein ligase TTC3/DZIP3 domain | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3B5Y4 | InterPro | 1110 | |||||
UniProtKB:A0A8M3BCR2 | InterPro | 1695 | |||||
UniProtKB:E7EYR3 | InterPro | 1694 |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | Fosmid | CH1073-446E18 | ZFIN Curated Data |
1 - 1 of 1
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_005172576 (1) | |||
Genomic | GenBank:CU633885 (1) | 40556 nt | ||
Polypeptide | UniProtKB:A0A8M3BCR2 (1) | 1695 aa |
- Horzmann, K.A., Reidenbach, L.S., Thanki, D.H., Winchester, A.E., Qualizza, B.A., Ryan, G.A., Egan, K.E., Hedrick, V.E., Sobreira, T.J.P., Peterson, S.M., Weber, G.J., Wirbisky-Hershberger, S.E., Sepúlveda, M.S., Freeman, J.L. (2018) Embryonic atrazine exposure elicits proteomic, behavioral, and brain abnormalities with developmental time specific gene expression signatures. Journal of proteomics. 186:71-82
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Lindeman, L.C., Reiner, A.H., Mathavan, S., Aleström, P., and Collas, P. (2010) Tiling histone h3 lysine 4 and 27 methylation in zebrafish using high-density microarrays. PLoS One. 5(12):e15651
1 - 3 of 3
Show