Gene

apela

ID
ZDB-GENE-090313-116
Name
apelin receptor early endogenous ligand
Symbol
apela Nomenclature History
Previous Names
  • ela
  • tdl
  • elabela (1)
  • ende
  • linc_tmem192 (1)
  • si:ch211-42i9.4
  • toddler
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Enables apelin receptor binding activity and hormone activity. Involved in heart development and mesendoderm migration. Acts upstream of with a positive effect on Kupffer's vesicle development. Acts upstream of or within with a positive effect on determination of heart left/right asymmetry and determination of liver left/right asymmetry. Acts upstream of or within several processes, including angioblast cell migration from lateral mesoderm to midline; apelin receptor signaling pathway; and gastrulation. Located in extracellular space. Is expressed in several structures, including Kupffer's vesicle; axis; heart primordium; hypoblast; and mesoderm. Orthologous to human APELA (apelin receptor early endogenous ligand).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
29 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With apela Human Ortholog
No data available
Associated With apela Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations