Gene

cnga1a

ID
ZDB-GENE-090312-66
Name
cyclic nucleotide gated channel subunit alpha 1a
Symbol
cnga1a Nomenclature History
Previous Names
  • si:dkey-22i16.2 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable cGMP binding activity; intracellularly cAMP-activated cation channel activity; and intracellularly cGMP-activated cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport and sensory perception of chemical stimulus. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of intracellular cyclic nucleotide activated cation channel complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel subunit alpha 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa4861Allele with one point mutationUnknownPremature StopENU
sa6600Allele with one point mutationUnknownPremature StopENU
sa14137Allele with one point mutationUnknownSplice SiteENU
sa18298Allele with one point mutationUnknownPremature StopENU
zko803aAllele with one deletionUnknownUnknownCRISPR
zko803bAllele with one deletionUnknownUnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-cnga1a (2)
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Human Disease
Associated With cnga1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 49 Alliance Retinitis pigmentosa 49 613756
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Associated With cnga1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
Domain IPR000595 Cyclic nucleotide-binding domain
Domain IPR005821 Ion transport domain
Domain IPR032406 Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
Family IPR050866 Cyclic nucleotide-gated cation channel
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Domain Details Per Protein
Protein Additional Resources Length Cyclic nucleotide-binding, conserved site Cyclic nucleotide-binding domain Cyclic nucleotide-binding domain superfamily Cyclic nucleotide-gated cation channel Cyclic nucleotide-gated channel, C-terminal leucine zipper domain Ion transport domain RmlC-like jelly roll fold
UniProtKB:B8JHY6 InterPro 697
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 1
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cnga1a-201 (1) Ensembl 2,094 nt
mRNA cnga1a-202 (1) Ensembl 2,594 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-22I16ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanCNGA14
Amino acid sequence comparison (1)
Phylogenetic tree (1)
Citations
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