Gene
tns2a
- ID
- ZDB-GENE-090312-163
- Name
- tensin 2a
- Symbol
- tns2a Nomenclature History
- Previous Names
-
- si:dkey-31e3.3
- tenc1a
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in negative regulation of insulin receptor signaling pathway. Predicted to be located in anchoring junction. Predicted to be active in focal adhesion. Orthologous to human TNS2 (tensin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000980 | SH2 domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR006020 | PTB/PI domain |
| Domain | IPR013625 | Tensin/EPS8 phosphotyrosine-binding domain |
| Domain | IPR014020 | Tensin phosphatase, C2 domain |
| Domain | IPR029023 | Tensin-type phosphatase domain |
| Domain | IPR033929 | Tensin, phosphotyrosine-binding domain |
| Domain | IPR035012 | Tensin-like, SH2 domain |
| Family | IPR051484 | Tensin Phosphatase |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C1-like domain superfamily | C2 domain superfamily | PH-like domain superfamily | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | PTB/PI domain | SH2 domain | SH2 domain superfamily | Tensin/EPS8 phosphotyrosine-binding domain | Tensin-like, SH2 domain | Tensin Phosphatase | Tensin phosphatase, C2 domain | Tensin, phosphotyrosine-binding domain | Tensin-type phosphatase domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AV49 | InterPro | 1593 | |||||||||||||||
| UniProtKB:A0A8M1QLC1 | InterPro | 1616 | |||||||||||||||
| UniProtKB:A0A8M2B8W0 | InterPro | 1606 | |||||||||||||||
| UniProtKB:A0A8M9PL00 | InterPro | 1616 | |||||||||||||||
| UniProtKB:A0A8M9PWP4 | InterPro | 1597 | |||||||||||||||
| UniProtKB:A0A8M9P5D1 | InterPro | 1593 | |||||||||||||||
| UniProtKB:A0A8M2B8V3 | InterPro | 1597 | |||||||||||||||
| UniProtKB:A0A8M9PWR1 | InterPro | 1606 |
Interactions and Pathways
No data available
Plasmids
No data available