Gene
ogdhb
- ID
- ZDB-GENE-090311-8
- Name
- oxoglutarate dehydrogenase b
- Symbol
- ogdhb Nomenclature History
- Previous Names
-
- si:ch211-229p19.3
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable oxoglutarate dehydrogenase (succinyl-transferring) activity. Acts upstream of or within heart contraction. Predicted to be located in nucleus. Predicted to be part of oxoglutarate dehydrogenase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in oxoglutarate dehydrogenase deficiency. Orthologous to human OGDH (oxoglutarate dehydrogenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| oxoglutarate dehydrogenase deficiency | Alliance | Oxoglutarate dehydrogenase deficiency | 203740 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001017 | Dehydrogenase, E1 component |
| Domain | IPR005475 | Transketolase-like, pyrimidine-binding domain |
| Domain | IPR031717 | 2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal |
| Domain | IPR032106 | 2-oxoglutarate dehydrogenase E1 component, N-terminal domain |
| Family | IPR011603 | 2-oxoglutarate dehydrogenase E1 component |
1 - 5 of 7 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | 2-oxoglutarate dehydrogenase E1 component | 2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal | 2-oxoglutarate dehydrogenase E1 component, N-terminal domain | Dehydrogenase, E1 component | Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily | Thiamin diphosphate-binding fold | Transketolase-like, pyrimidine-binding domain |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7EZ05 | InterPro | 1023 | |||||||
| UniProtKB:A0A8M9PUH2 | InterPro | 1020 |
1 - 2 of 2
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-229P19 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-259K14 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001338145 (1) | 3493 nt | ||
| Genomic | GenBank:CT956056 (1) | 151889 nt | ||
| Polypeptide | UniProtKB:E7EZ05 (1) | 1023 aa |