Gene
card14
- ID
- ZDB-GENE-090310-1
- Name
- caspase recruitment domain family, member 14
- Symbol
- card14 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have CARD domain binding activity. Predicted to be involved in regulation of apoptotic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in pityriasis rubra pilaris and psoriasis 2. Is expressed in gill and spleen. Orthologous to human CARD14 (caspase recruitment domain family member 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chang et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pityriasis rubra pilaris | Alliance | Pityriasis rubra pilaris | 173200 |
| psoriasis 2 | Alliance | Psoriasis 2 | 602723 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CARD domain | Death-like domain superfamily | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|
|
UniProtKB:A0A8N7T7Y7
|
985 | ||||
|
UniProtKB:A0A8M9Q0C3
|
985 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
card14-201
(1)
|
Havana | 4099 nt |
Interactions and Pathways
No data available
Plasmids
No data available